The Australia Research Council Centre of Excellence for Nanoscale BioPhotonics is a $40M investment by the ARC, state governments, academic institutions and industry to explore novel light based sensing technologies that are to created "windows into the body" to sense the previously unsensable. How many new terms can we use in the first sentence of a conference abstract? Apparently lots! But if you are interested, then you will love this session, because the basic understanding of the principals of these novel sensing modalities will be introduced and explained. Importantly, the relevance of these technologies and experimental approaches have for biology will be explored.